Colonel Catalin Ticulescu was the first commander of the first NATO Headquarters in Romania.Under the command of Colonel Ticulescu and alongside the Host Nation, NFIU Romania reached Initial Capability in January 2016 and Final Capability during the Warsaw NATO Summit, in July 2016. Together with the NFIU Romania multinational team, Colonel Ticulescu set the foundation for the Host Nation coordination and cooperation procedures, which were tested and validated during the largest NATO exercise in Romania to date, Noble Jump 2017.

Lieutenant Colonel Emil Bobocea was acting commander of NATO Force Integration Unit between August 2017 and March 2018. While in office, Lieutenant Colonel Emil Bobocea has ensured continuity and contributed to improving the relationship with Host Nation and with other NATO Command Structure (NCS) and NATO Force Structure (NFS) Headquarters.

Colonel Cornel Tonea-Bălan was acting commander of NATO Force Integration Unit between March 2018 and February 2019. Under his command, the NFIU continued to build relationships with Host Nation and with other relevant structures.

Lieutenant colonel Marius Chiriță was acting commander of NATO Force Integration Unit between March-June 2019. Under his command, NFIU ROU was recertified as a NATO unit able to fulfil its assigned mission.

Lieutenant Colonel Sorin Gheorghe Șoană ensured the command of the NATO Integration Unit, between June 2019 and September 2021. During his time as Commander, NFIU ROU celebrated 5 years since its establishment on September 1, 2020. Lieutenant Colonel Șoană continued improving the relationship with the Host Nation and other structures of interest, and during the Steadfast Defender 21 exercise, once again it demonstrated that NFIU ROU is ready to carry out its assigned missions in any circumstance.

Colonel Cristian Ivănescu ensured the command of the NATO Integration Unit, between 01 November 2021 and 15 December 2022.
During his time as Commander, he supported together with his staff the deployment process of the French Battle Group in Romania, once again demonstrating that NFIU ROU is ready to carry out its assigned missions in any circumstance.
Under his command, on September 1, 2022, NFIU ROU celebrated 7 years since its establishment.
Colonel Cristian Ivănescu continued improving and consolidating the relationship with the Host Nation and other structures of interest.